| 51 Wins (38 knockouts, 13 decisions), 3 Losses (2 by knockout, 1 by decision), 2 Draws [96] |
| Res. | Opponent | Type | Rd | Date | Location | Notes |
| N/A |  Antonio Margarito | - | - (12) | 2010-11-13 |  Cowboys Stadium, Arlington, United States | Vacant WBC Super Welterweight World Title on the line. |
| Win |  Joshua Clottey | UD | 12 (12) | 2010-03-13 | Cowboys Stadium, Arlington, United States | Retained WBO Welterweight World Title. |
| Win |  Miguel Ángel Cotto | TKO | 12 (12) | 2009-11-14 | MGM Grand Garden Arena, Las Vegas, United States | Won WBO Welterweight World Title and WBC Diamond Belt. |
| Win |  Ricky Hatton | KO | 2 (12) | 2009-05-02 | MGM Grand Garden Arena, Las Vegas, United States | Won IBO and The Ring Light Welterweight World Titles. |
| Win | Oscar De La Hoya | TKO | 8 (12) | 2008-12-06 | MGM Grand Garden Arena, Las Vegas, United States | A non-title fight, fought at Welterweight. |
| Win | David Díaz | TKO | 9 (12) | 2008-06-28 | Mandalay Bay, Las Vegas, United States | Won WBC Lightweight World Title. |
| Win | Juan Manuel Márquez | SD | 12 (12) | 2008-03-15 | Mandalay Bay, Las Vegas, United States | Won WBC and vacant The Ring Super Featherweight World Titles. |
| Win | Marco Antonio Barrera | UD | 12 (12) | 2007-10-06 | Mandalay Bay, Las Vegas, United States | Retained WBC Super Featherweight International Title. |
| Win | Jorge Solís | KO | 8 (12) | 2007-04-14 | Alamodome, San Antonio, United States | Retained WBC Super Featherweight International Title. |
| Win | Érik Morales | KO | 3 (12) | 2006-11-18 | Thomas and Mack Center, Las Vegas, United States | Retained WBC Super Featherweight International Title. |
| Win | Óscar Larios | UD | 12 (12) | 2006-07-02 |  Araneta Coliseum, Quezon City, Philippines | Retained WBC Super Featherweight International Title. |
| Win | Érik Morales | TKO | 10 (12) | 2006-01-21 | Thomas and Mack Center, Las Vegas, United States | Retained WBC Super Featherweight International Title. |
| Win | Héctor Velázquez | TKO | 6 (12) | 2005-09-10 | Staples Center, Los Angeles, United States | Won vacant WBC Super Featherweight International Title. |
| Loss | Érik Morales | UD | 12 (12) | 2005-03-19 | MGM Grand Garden Arena, Las Vegas, United States | Vacant WBC International and IBA Super Featherweight Title match. |
| Win |  Fahsan Por Thawatchai | TKO | 4 (12) | 2004-12-11 | Fort Bonifacio Global City, Taguig City, Philippines | Retained The Ring Featherweight World Title. |
| Draw | Juan Manuel Márquez | Draw | 12 (12) | 2004-05-08 | MGM Grand Garden Arena, Las Vegas, United States | Controversial Draw. WBA and IBF Featherweight World Title match. |
| Win | Marco Antonio Barrera | TKO | 11 (12) | 2003-11-15 | Alamodome, San Antonio, United States | Won The Ring Featherweight World Title. |
| Win | Emmanuel Lucero | KO | 3 (12) | 2003-07-26 | Olympic Auditorium, Los Angeles, United States | Retained IBF Super Bantamweight World Title. |
| Win |  Serikzhan Yeshmagambetov | TKO | 5 (10) | 2003-03-15 | Rizal Park, Manila, Philippines |
|
| Win | Fahprakorb Rakkiatgym | KO | 1 (12) | 2002-10-26 | Rizal Memorial College Gym, Davao City, Philippines | Retained IBF Super Bantamweight World Title. |
| Win |  Jorge Eliecer Julio | TKO | 2 (12) | 2002-06-08 | The Pyramid, Memphis, United States | Retained IBF Super Bantamweight World Title. |
| Draw |  Agapito Sánchez | TD | 6 (12) | 2001-11-10 | Bill Graham Civic Auditorium, San Francisco, United States | WBO and IBF Super Bantamweight World Title match. |
| Win |  Lehlohonolo Ledwaba | TKO | 6 (12) | 2001-06-23 | MGM Grand Garden Arena, Las Vegas, United States | Won IBF Super Bantamweight World Title. |
| Win | Wethya Sakmuangklang | KO | 6 (12) | 2001-04-28 | Kidapawan City, Cotabato, Philippines | Retained WBC Super Bantamweight International Title. |
| Win |  Tetsutora Senrima | TKO | 5 (12) | 2001-02-24 | Manila, Philippines | Retained WBC Super Bantamweight International Title. |
| Win |  Nedal Hussein | TKO | 10 (12) | 2000-10-14 | Ynares Center, Antipolo City, Philippines | Retained WBC Super Bantamweight International Title. |
| Win |  Seung-Kon Chae | TKO | 1 (12) | 2000-06-28 | Araneta Coliseum, Quezon City, Philippines | Retained WBC Super Bantamweight International Title. |
| Win | Arnel Barotillo | KO | 4 (12) | 2000-03-04 | Ninoy Aquino Stadium, Manila, Philippines | Retained WBC Super Bantamweight International Title. |
| Win | Reynante Jamili | KO | 2 (12) | 1999-12-18 | Elorde Sports Complex, Parañaque City, Philippines | Won WBC Super Bantamweight International Title. |
| Loss | Medgoen Singsurat | KO | 3 (12) | 1999-09-17 | Pakpanag Metropolitan Stadium, Nakhon Si Thammarat, Thailand | He was overweight at weigh-in. Lost WBC Flyweight World Title. |
| Win | Gabriel Mira | TKO | 4 (12) | 1999-04-24 | Araneta Coliseum, Quezon City, Philippines | Retained WBC Flyweight World Title. |
| Win | Todd Makelim | TKO | 3 (10) | 1999-02-20 | Kidapawan City, Cotabato, Philippines |
|
| Win | Chatchai Sasakul | KO | 8 (12) | 1998-12-04 | Tonsuk College Ground, Phutthamonthon, Thailand | Won WBC Flyweight World Title. |
| Win | Shin Terao | TKO | 1 (10) | 1998-05-18 | Korakuen Hall, Tokyo, Japan |
|
| Win | Panomdej Ohyuthanakorn | KO | 1 (12) | 1997-12-06 | South Cotabato Stadium, Koronadal City, South Cotabato, Philippines | Retained OPBF Flyweight Title. |
| Win | Melvin Magramo | UD | 10 (10) | 1997-09-13 | Cebu City, Philippines |
|
| Win | Chokchai Chockvivat | KO | 5 (12) | 1997-06-26 | Mandaluyong City, Philippines | Won OPBF Flyweight Title. |
| Win | Ariel Austria | TKO | 6 | 1997-05-30 | Almendras Gym, Davao City, Philippines |
|
| Win | Wook-Ki Lee | KO | 1 (10) | 1997-04-24 | Makati City, Philippines |
|
| Win | Mike Luna | KO | 1 (10) | 1997-03-03 | Muntinlupa City, Philippines |
|
| Win | Sung-Yul Lee | TKO | 2 | 1996-12-28 | Muntinlupa City, Philippines |
|
| Win |  Ippo Gala | TKO | 2 | 1996-07-27 | Mandaluyong City, Philippines |
|
| Win | Bert Batiller | TKO | 4 | 1996-06-15 | Mandaluyong City, Philippines |
|
| Win | John Medina | TKO | 4 | 1996-05-05 | Manila, Philippines |
|
| Win | Marlon Carillo | UD | 10 (10) | 1996-04-27 | Manila, Philippines |
|
| Loss | Rustico Torrecampo | KO | 3 | 1996-02-09 | Mandaluyong City, Philippines | He had not made the weight so he was forced to use heavier gloves. |
| Win | Lito Torrejos | UD | 5 | 1996-01-13 | Parañaque City, Philippines |
|
| Win | Rolando Toyogon | UD | 10 (10) | 1995-12-09 | Manila, Philippines |
|
| Win | Rudolfo Fernandez | TKO | 3 (10) | 1995-11-11 | Mandaluyong City, Philippines |
|
| Win | Renato Mendones | TKO | 2 (8) | 1995-10-21 | Puerto Princesa City, Palawan, Philippines |
|
| Win | Lolito Laroa | UD | 8 (8) | 1995-10-07 | Makati City, Philippines |
|
| Win | Armando Rocil | KO | 3 | 1995-09-16 | Mandaluyong City, Philippines |
|
| Win | Acasio Simbajon | UD | 6 (6) | 1995-08-03 | Mandaluyong City, Philippines |
|
| Win | Dele Decierto | TKO | 2 | 1995-07-01 | Mandaluyong City, Philippines |
|
| Win | Rocky Palma | UD | 6 (6) | 1995-05-01 | Montano Hall, Cavite City, Philippines |
|
| Win | Pinoy Montejo | UD | 4 (4) | 1995-03-18 | Mindoro Occidental, Philippines |
|
| Win | Edmund Enting Ignacio | UD | 4 (4) | 1995-01-22 | Mindoro Occidental, Philippines | Professional boxing debut at Light Flyweight |
